One of Illumina’s newest series of products is the exome array with ∼240 000 SNPs, which, depending on the version, focuses on exonic variants, with an additional 24.8% of the SNPs from the GWAS catalog. Illumina has a long history of designing and producing genotyping arrays, with many of them powering important GWAS. Genotyping microarrays are also referred to as single-nucleotide polymorphism (SNP) arrays, and have been the tool of choice for genome-wide association studies (GWASs) for the past 15 years. However, the decline of the gene expression microarray has coincided with a rising market for genotyping arrays thanks to new strategies and products set forth by Illumina. HTS-based RNA sequencing offers competitive prices and numerous analytical advantages, such as the ability to detect structural variants and novel transcripts. However, since the introduction of high-throughput sequencing (HTS), the application of gene expression quantification by microarray has gradually diminished. ![]() One of the early representative high-throughput genomic technologies is the microarray, which was the dominate technology for gene expression quantification and genotyping. High-throughput genomic technology has revolutionized the landscape of biomedical research.
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